Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume
نویسندگان
چکیده
منابع مشابه
Enicostemma littorale Blume aqueous extract improves the antioxidant status in alloxan-induced diabetic rat tissues.
This study investigates the effect of oral administration of an aqueous Enicostemma littorale whole plant extract on antioxidant defense in alloxan-induced diabetes in rats. A significant increase in blood glucose and increased concentration of thiobarbituric acid reactive substances (TBARS) and hydroperoxides (HP) in liver, kidney and pancreas were observed in alloxan diabetic rats. Decreased ...
متن کاملProtective Effect of Enicostemma littorale Blume Methanolic Extract on Gentamicin-Induced Nephrotoxicity in Rats
Problem statement: The Amino glycoside antibiotics cause drug induced nephrotoxicity at therapeutic doses and thus limits the use clinically. Oxidative stress is one of the main reasons for the development of nephrotoxicity. Approach: In light of this the aim of the present study was to investigate the role of mitochondrial as well as post-mitochondrial oxidative stress in the development of Ge...
متن کاملHypoglycemic effect of aqueous extract of Enicostemma littorale Blume (chhota chirayata) on alloxan induced diabetes mellitus in rats.
The whole plant aqueous extract of E. littorale was tested for its hypoglycemic activity on normoglycemic, hyperglycemic and alloxan induced diabetic rats. Blood sugar lowering activity was not observed in normoglycemic and glucose loaded hyperglycemic rats in the short time experiment. But in case of diabetic rats, the fall of blood sugar after 30 days treatment with the aqueous extract was fo...
متن کاملAntidepressant Activity of Enicostemma littorale Blume in Shp2 (Protein Tyrosine Phosphatase)-inhibited Animal Model of Depression
BACKGROUND The objective of this study is to develop a new animal model based on signaling pathways to understand the pathophysiology, therapy of depression, and to investigate the antidepressant activity of Enicostemma littorale which is not yet established. METHODS Animal models of depression were raised by physical methods and administration of methyl isobutyl ketone (100 mg/kg b.w., i.p.,...
متن کاملEstimation of Biomass Contents and Phytoconstituent Analysis of Enicostemma Littorale Blume
Enicostemma littorale Blume is a medicinal plant commonly called as whitehead. Traditionally, the plant is used in the treatment of large number of human ailments such as in hypoglycemic, lowering the blood glucose level, as a potent anti-diabetic and antioxidant activity. Currently, the scientific research is going on to prove its medicinal value. Hence, to evaluate the phytoconstituents and t...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Biomedicine
سال: 2011
ISSN: 2221-1691
DOI: 10.1016/s2221-1691(11)60084-1